A comparision of left ventricular functions after acute myocardial infarction receiving different reperfusion therapy

Authors : İhsan DURSUN

Pages : 1-6

View : 27 | Download : 7

Publication Date : 2019-10-25

Article Type : Research Paper

Abstract :Background : It is demonstrated that primary angioplasty is more effective than thrombolytic therapy on the clinical outcomes in ST- segment elevation acute myocardial infarction insert ignore into journalissuearticles values(STEMI);. The aim of this study was to compare the effects of reperfusion therapies on left ventricular systolic and diastolic functions. Methods : We assigned 114 patients insert ignore into journalissuearticles values(19 female, mean age 60.2 ± 10.7 years, and 95 male, mean age 53.6 ± 11.0 years); with first STEMI treated with primary angioplasty insert ignore into journalissuearticles values(n=54); or thrombolytic drug therapy insert ignore into journalissuearticles values(n=60); in accordance with selection criteria. Assesment of LV systolic function was done by wall motion score index insert ignore into journalissuearticles values(WMSI); and left ventricular ejection fractioninsert ignore into journalissuearticles values( LVEF);. Left ventricular diastolic function was evaluated by the pulsed Doppler technique Results : WMSI was significantly lower in angioplasty group  insert ignore into journalissuearticles values(1.31 ± 0.30); compared to thrombolysis group insert ignore into journalissuearticles values(1.45 ± 0.40);  insert ignore into journalissuearticles values(P<0.01);. LVEF did not differ between treatment groups insert ignore into journalissuearticles values(50 ± 9 % vs 47 ± 8 %,  P>0.05);. The frequency of diastolic dysfunction tended to lower in angioplasty group but the difference was not significant insert ignore into journalissuearticles values(50% vs 62%, P>0.05);. Nevertheless, rates of restrictive filling pattern cases was significantly higher in thrombolysis group insert ignore into journalissuearticles values( 7% vs 22%, P<0.05 );. There was a significant difference for E/A ratio between two groups insert ignore into journalissuearticles values(0.99± 0.38 versus 1.20± 0.60, P<0.05);. Conclusions : The results showed that the left ventricular systolic and diastolic functions were preserved with STEMI treated by primary angioplasty. This may contribute to better clinical outcomes in patients with STEMI treated with primary angioplasty.  
Keywords : Primary angioplasty, acute myocardial infarction, left ventricular function, restrictive filling pattern

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