Evaluation of colposcopy results for patients who are HPV DNA positive in KETEM

Authors : Murat ALAN, Muhammet Ali ORUC, Mustafa KURT, Yasemin ALAN, Muzaffer SANCİ

Pages : 35-42

View : 31 | Download : 10

Publication Date : 2019-12-25

Article Type : Research Paper

Abstract :We evaluated colposcopy and postoperative biopsy results in cases referred to our oncology center from the Cancer Early Diagnosis and Treatment Center insert ignore into journalissuearticles values(KETEM); due to Human Papilloma Virus insert ignore into journalissuearticles values(HPV); positivity and/or cervical pre- malignant lesion insert ignore into journalissuearticles values(CPL);. A total of 1230 female patients who were admitted to our Oncology outpatient clinic between January 2016 and December 2017 with positive HPV DNA screening tests from KETEM regardless of whether they had cervical premalignant lesion or not as a result of Papanicolaou smear insert ignore into journalissuearticles values(PAP smear); were included in the study. Colposcopy was performed in all cases and cervical biopsy was performed in patients who had suspicious lesions. Nosignificant relationship was found between smoking status, educational status and financial status and HPV DNA screening test results insert ignore into journalissuearticles values(p = 0.123, p = 0.201, p = 0.244, respectively);. The sensitivity of colposcopy to detect cervical pre- malignant lesions was 99.2% and positive predictive value insert ignore into journalissuearticles values(PPD); was 74.1%. In determining the cervical premalignant lesions, the sensitivity of smear was41.3% and its specificity was 66.5%, PPV insert ignore into journalissuearticles values(positive predictive value); was 78.1%and NPV insert ignore into journalissuearticles values(negative predictive value); was 28.2%. In our study, the sensitivity of the HPV test to determine cervical premalignant lesions was 93.1%, PPV was74%, specificity 86% and NPV was 30%. The accuracy of HPV types in deter-mining CPLs was found to be insert ignore into journalissuearticles values(530 + 17);/776=71.4%. Positivity on the HPV DNA screening test is the leading risk factor for cervical cancer development. As a result, the first step in family medicine and KETEM activities is to reducethe frequency of these cancers and the complications related to the disease by increasing information and screening examination applications.
Keywords : KETEM, Cervical Premalign Lesion, Colposcopy

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