Propofol-ketamine versus propofol-tramadol sedation in children undergoing gastrointestinal endoscopy

Authors : Yasemin USTUN, Ersin KÖKSAL, Cengiz KAYA, Sezgin BİLGİN, Burhan DOST, Gönül DİNLER ÇALTEPE

Pages : 1-4

View : 45 | Download : 9

Publication Date : 2021-01-26

Article Type : Research Paper

Abstract :Numerous combinations of drugs are used for sedation in upper gastrointestinal endoscopies. The aim of this study was to compare the quality of two sedation regimens in upper gastrointestinal endoscopy performed on pediatric patients. After the study approval by the local ethics committee of Ondokuz Mayıs University Hospital, written informed consent was obtained from parents. Eighty patients between the ages of 1 and 18 were randomized into two groups. Group K insert ignore into journalissuearticles values(n=40); received propofol 1 mg/kg + 1 mg/kg ketamine intravenously. Group T insert ignore into journalissuearticles values(n=40); received propofol 1 mg/kg + 1 mg/kg tramadol intravenously. In both groups, additional propofol insert ignore into journalissuearticles values(0.5 mg/kg); was administrated when a patient showed signs of discomfort, in order to maintain a Ramsey Sedation Scale of 4 to 5. In Group K, additional propofol requirements were significantly lower compared to Group T insert ignore into journalissuearticles values(p=0.003);. Group K had significantly higher sedation scores than Group T at 3rd min. insert ignore into journalissuearticles values(p=0.028); and 20th min. insert ignore into journalissuearticles values(p=0.015);. Recovery time increased significantly in Group K insert ignore into journalissuearticles values(p=0.002);. Although there was no difference between two groups concerning the propofol consumption, both groups required additional propofol and tramadol resulted in a shorter recovery time compared to ketamine.
Keywords : Anesthesia Recovery Period, Deep Sedation, Digestive System Endoscopy, Pediatric Nursing

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