Evaluation of serum levels of Copper and Selenium in H .pylori positive and negative gastritis patients

Authors : Vahid HAMİDİ, Mohammad RANAEİ, Nahid NEAMATİ, Javad SHOKRİ, Karimollah HAJİAN, Abbas MOSAPOUR, Mehdi SOLTANZADEH, Mehdi TOURANİ, Hadi PARSİAN

Pages : 182-186

View : 43 | Download : 9

Publication Date : 2021-04-03

Article Type : Research Paper

Abstract :Background: Helicobacter pylori insert ignore into journalissuearticles values(H. pylori); infection can result in various complications, included micronutrient variations, nutritional impairment, gastric tissue damages and oxidative stress. The present study aimed to evaluate serum variations of Cu and Se in H. pylori infected individuals. Materials and methods: A prospective case-control study was performed on 69 participants with abdominal pains insert ignore into journalissuearticles values(40 patients with H. pylori gastritis versus 29 control group);. Serum levels of Cu and Se were measured using Atomic Absorption Spectrophotometer. Statistical analysis was performed using SPSS software. Comparisons of elements between included groups were done using independent sample t-test. Subgroup analysis between male and female insert ignore into journalissuearticles values(with or without H. pylori); was performed using one way analysis of variance. Correlation between serum Cu and Se was assessed using Pearson’s correlation test. The p-value levels less than 0.05 were considered as significant. Results: There were no significant differences in serum levels of Cu and Se between H. pylori positive and negative persons. In male with H. pylori, Se levels were 38.4% higher than control male insert ignore into journalissuearticles values(p-value=0.03);. A positive and significant correlation was observed between serum Cu and Se levels insert ignore into journalissuearticles values(r = 0.51, P-value = 0.024);. Conclusion: Although no statistic difference was observed in serum Cu and Se levels, the significant correlation between measured elements represent as good evidence for some discrepancies. Given the importance of well controlled micronutrients in whole body health, especially in high risk H. pylori patients, more studies are needed to clarify the exact relation of these and other trace elements with H. pylori outcomes.
Keywords : Copper Cu, Helicobacter pylori H pylori, Selenium Se, gastroduodenal complication

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