- Journal of Experimental and Clinical Medicine
- Volume:38 Issue:2s
- Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants
Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants
Authors : Şencan ACAR, Ahmet EMİNLER
Pages : 33-37
View : 39 | Download : 7
Publication Date : 2021-03-18
Article Type : Review Paper
Abstract :Direct-acting oral anticoagulants include dabigatran, which is a thrombin inhibitor, and rivaroxaban, apixaban, and edoxaban, which are anti-Xa agents. These are administered in the secondary prophylaxis and treatment of venous thromboembolism insert ignore into journalissuearticles values(VTE); and pulmonary embolism insert ignore into journalissuearticles values(PE);, in the prophylaxis of VTE that may develop after major elective orthopedic surgery, in reducing stroke and systemic embolism that may occur in non-valvular atrial fibrillation, whereas its use in acute coronary syndrome is still controversial. Although it is specified that direct-acting oral anticoagulants are as effective as heparin therapy and reduce the risk of bleeding due to all causes, many important studies have also reported that they increase the risk of gastrointestinal system insert ignore into journalissuearticles values(GIS); bleeding.Keywords : Gastrointestinal Bleeding, Direct Acting Oral Anticoagulants, Endoscopy
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