The evaluation of the triglyceride glucose index in symptomatic patients with high suspicion of coronary artery disease: a single center study

Authors : Sara ÇETİN ŞANLIALP, Gokay NAR

Pages : 599-603

View : 33 | Download : 11

Publication Date : 2021-10-09

Article Type : Research Paper

Abstract :Triglyceride glucose index insert ignore into journalissuearticles values(TyG); plays an important role in metabolic syndrome insert ignore into journalissuearticles values(MetS);, which predisposes to the development of cardiovascular diseases insert ignore into journalissuearticles values(CVD);. Mostly, the association between the TyG index and coronary artery disease insert ignore into journalissuearticles values(CAD); has been investigated in healthy individuals on long-term follow-up or in asymptomatic patients with a mild and mild-moderate cardiovascular risk profile. However there are few studies evaluating the association of TyG index with CAD in symptomatic patients. In hence, we aimed to determine the role of the TyG index in the presence and severity of CAD in symptomatic patients with high suspicion of CAD in this study. 100 patients who underwent coronary angiography were included and the patients were divided into two groups according to the presence of CAD. TyG index was calculated by the formula Ln [fasting triglycerides insert ignore into journalissuearticles values(mg/dl);xfasting glucose insert ignore into journalissuearticles values(mg/dl);/2]. The severity of CAD was assessed by angiographic risk scores GENSINI, SYNTAX I, and the number of diseased vessels. TyG index did not differ significantly between patients with and without CAD. Also, there was no significant correlation between TyG index and GENSINI, SYNTAX I, and the number of diseased vessels. insert ignore into journalissuearticles values(for all p>0.05); In multiple logistic regression analysis, the only independent predictor of CAD was age. insert ignore into journalissuearticles values(p=0.03, OR=1.048, 95% CI=1.004-1.094); In conclusion, TyG index may not be a useful marker for predicting the presence or severity of CAD. According to the results of this study, age is the only predictor of CAD independent of all causes.
Keywords : Coronary artery disease, GENSINI, SYNTAX I, Triglyceride glucose index

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