The role of platelet mass index in the prediction of preeclampsia full

Authors : Cuma TAŞIN, Nezaket KADIOĞLU, Revan Sabri ÇİFTÇİ, Ayhan COSKUN, Hakan AYTAN

Pages : 221-225

View : 43 | Download : 14

Publication Date : 2022-01-01

Article Type : Research Paper

Abstract :To assess the possible roles of platelet indices including platelet mass index insert ignore into journalissuearticles values(PMI);, platelet count insert ignore into journalissuearticles values(PC);, mean platelet volume insert ignore into journalissuearticles values(MPV); and PC/MPV in prediction of preeclampsia. 190 pregnant women diagnosed with preeclampsia and 100 healthy uncomplicated control patients were included in this retrospective study. Age, gestational week, fetal weight, alanine transaminase insert ignore into journalissuearticles values(ALT);, aspartate transaminase insert ignore into journalissuearticles values(AST);, creatinine, blood urea nitrogen insert ignore into journalissuearticles values(BUN);, complete blood count parameters and platelet indices were compared. ROC curve was applied to analyze the cut-off values of the significantly differing parameters for prediction of preeclampsia. Preeclamptic patients gave birth significantly earlier than the controls. In preeclamptic patients, the mean values of PC, PC / MPV and PMI were significantly lower than the control group. Although mean MPV values were lower in preeclampsia patients, the difference was not significant. The cut-off values of PC, PC/MPV and PMI were found to be 207,500, 18448.16 and 2411.75 with a-sensitivity/specificity of 45.3%/ 44.3%, 42.2%/ 42.6% and 44.1%/ 44.3%, respectively. Indices such as PC, PC / MPV and PMI changed significantly in preeclampsia. Although they have low sensitivity and specificity, these indices can be combined with other parameters and used in the prediction of preeclampsia.
Keywords : Mean Platelet Volume, Platelet Indices, Platelet Mass Index, Preeclampsia

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