Comparison of quality of life, depression and fatigue in patients with psoriasis and psoriatic arthritis

Authors : Sertaç KETENCİ, Bora UZUNER, Ayhan BİLGİCİ

Pages : 174-179

View : 35 | Download : 10

Publication Date : 2022-01-01

Article Type : Research Paper

Abstract :Psoriatic arthritis insert ignore into journalissuearticles values(PsA); is a chronic inflammatory multisystemic disease. Limitations due to skin and joint involvement of the patients; can lead to negativie suffix in emotional state, social and physical activities. The aim of this study is to investigate the effects of parameters such as skin joint involvement and disease severity on factors such as fatigue, quality of life, depression, etc. in psoriasis and PsA patients. Thirty-four psoriasis and 48 PsA patients matched with each other in terms of age, sex, and other factors were included in the study. Disease severity was measured by Psoriasis Area Severity Index insert ignore into journalissuearticles values(PASI);, Nail Psoriasis Severity Index insert ignore into journalissuearticles values(NAPSI);, Disease Activity in Psoriatic Arthritis insert ignore into journalissuearticles values(DAPSA); and Bath Ankylosing Spondylitis Disease Activity Index insert ignore into journalissuearticles values(BASDAI); scores. In order to determine the depression status, quality of life and fatigue levels of the patients, respectively; Beck Depression Inventory insert ignore into journalissuearticles values(BDI);, Health Assessment Questionnaire insert ignore into journalissuearticles values(HAQ); and Functional Assessment of Chronic Illness Therapy - fatigue scale insert ignore into journalissuearticles values(FACIT); scores were used. SPSS 17 for statistical evaluation insert ignore into journalissuearticles values(SPSS Inc. Released 2007. SPSS for Windows, Version 17.0. Chicago, SPSS Inc.); software package was used for analyses. Written informed consent was obtained from all patients who were enrolled to the study. PsA patients were found to have worse quality of life scores than psoriasis patients who were similar in terms of age, gender and other demographic characteristics. insert ignore into journalissuearticles values(0.22±0.36-0-0.48±0.52 p=0.017 respectively);. There was a strong correlation between DAPSA scores and HAQ scores of the cases in the PsA group insert ignore into journalissuearticles values(r:0 ,615 p<0.05);. Likewise, disease activity measured by DAPSA was found to have moderate correlation with FACIT score, and weak but statistically significant correlation with BDI score. insert ignore into journalissuearticles values(r: -0.578 p<0.05 and r:0.346 p<0.001, respectively);. No correlation was found between NAPSI-PASI scores and HAQ, BDI - FACIT scores in both the psoriasis and PsA groups. Both psoriasis and PsA affect the quality of life, and our findings suggest that this effect is more pronounced in PsA patients. Our study supports that; the disease severity in PsA patients is related to depression, bad quality of life and fatigue level.
Keywords : psoriasis, arthritis, disease activity, inflammation

ORIGINAL ARTICLE URL