The Practice of Covid-19 Vaccination in Patients Bleeding Disorders

Authors : Memiş Hilmi ATAY, Engin KELKİTLİ

Pages : 767-769

View : 39 | Download : 11

Publication Date : 2022-08-30

Article Type : Research Paper

Abstract :Objective: Subcutaneous injections are recommended instead of intramuscular for patients with bleeding disorders to avoid bleeding complications. This study aimed to determine whether the intramuscular administration of COVID-19 vaccines would increase bleeding-associated complications in patients with bleeding disorders who were followed in our clinic. Materials and Methods: Data of the 47 patients with bleeding disorders over the age of 18 who were followed clinic of our center and screened between March 1, 2020, and 31 December 2021. Patient data were extracted from the hospital’s electronic information system, which included their age, gender, type of bleeding disorder, factor levels, and whether they received prophylaxis. Patients were interviewed regarding the type of vaccine they received, the time for which compression was applied to their injection site, whether they received factor replacement before and after the injection, and whether there were any complications following the injection either in person Results: Thirty-nine patients who were vaccinated against COVID-19 were included in the study. All the patients included in the study were male. The mean age of the patients was 39.05 insert ignore into journalissuearticles values(18–73 years);. Factor VIII deficiency constituted 79.4%, factor XI 10.3%, other bleeding disorders factor 10.3 % of the cases. The patients with the bleeding disorder had a mean factor level of 2.02 insert ignore into journalissuearticles values(0–9);. Twenty-nine insert ignore into journalissuearticles values(74.4%); patients were on regular factor prophylaxis for their bleeding disorder. In terms of the period of compression following the injection, 6 insert ignore into journalissuearticles values(15.4%); patients had applied compression for 10 min, 4 insert ignore into journalissuearticles values(10.3%); for 5–10 min, and 29 insert ignore into journalissuearticles values(73.4%); for less than 5 min to the injection site. Two insert ignore into journalissuearticles values(5.1%); patients developed ecchymosis after the first vaccine dose on the injection arm. Conclusion: The results of this study demonstrate that the rate of bleeding complications remains low in patients with bleeding disorders if they receive intramuscular vaccination after the necessary precautions are taken
Keywords : bleeding disorders, Covid 19, vaccination, complication

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