- Journal of Experimental and Clinical Medicine
- Volume:39 Issue:4
- Drug repositioning approach to target viral and host cells in the terms of COVID-19 treatment: A re...
Drug repositioning approach to target viral and host cells in the terms of COVID-19 treatment: A review of in vivo experiments and clinical studies
Authors : Ali SHAHALİ, Vajihe AKBARİ, Rasool SOLTANİ, Shirinsadat BADRİ, Rashid ALİJANİ ARDESHİR
Pages : 1255-1269
View : 25 | Download : 7
Publication Date : 2022-10-29
Article Type : Review Paper
Abstract :While the COVID-19 pandemic is expanding at an alarming rate, there is currently no treatment option for this disease. Therefore, it is necessary to find an effective treatment special for hospitalized COVID-19 patients at the earliest possible time. One of the promising options which should be investigated is the possible effects of old drugs or drug repositioning. This strategy has less risk with more economical advantages and can be beneficial for the long-term control of this pandemic. Our study aimed to give an overview, update the current status of drugs candidates insert ignore into journalissuearticles values(both virus-targeting and host-targeting drugs); for repurposing in COVID-19 infection, and assess the possible mechanism of their effect, in vivo antiviral efficacy, and clinical studiesKeywords : Coronavirus Disease 2019 COVID 19, Drug repurposing, therapeutic, pandemics
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