Correlation of blood glucose and prostatic-related parameters in patients with prostate enlargement

Authors : Ida Bagus Gde Tirta Yoga YATİNDRA, Anak Agung Sagung Mirah PRABANDARİ, Pande Made Wisnu TİRTAYASA, Ida Bagus Tatwa YATİNDRA, Anak Agung Ngurah Oka DİATMİKA, Kadek Cindy MERNİKA
Pages : 90-93
View : 187 | Download : 303
Publication Date : 2023-03-18
Article Type : Research Paper
Abstract :Enlarged prostate, either in benign prostatic hyperplasia or prostate cancer is the predominant urological disease affecting older men. Metabolic syndrome including high blood glucose was considered to take part in the development of prostate enlargement, although their association is still unclear. This study aims to investigate the correlation between blood glucose with prostatic-related parameters. A cross-sectional study was conducted involving 91 men with prostate enlargement from Urology Polyclinic, Tabanan Hospital, Bali Province, Indonesia. Prostatic-related parameters collected include patient’s international prostate symptoms score using the questionnaire, prostate-specific antigen and random blood glucose analysis from serum blood sample, and prostate volume determined with transabdominal ultrasonography. Patient’s mean age was 65.4 ± 10 years, mean prostate volume 52.7 ± 26 ml, mean prostate-specific antigen insert ignore into journalissuearticles values(PSA); 9.2 ± 17 ng/ml, mean international prostatic symptoms score insert ignore into journalissuearticles values(IPSS); 14.31 ± 7.1, mean random blood glucose 121.1 ± 40.5 mg/dl. This study found weak positive correlation between random blood glucose and prostate volume insert ignore into journalissuearticles values(r=0.269; p=0.01);. PSA and prostate volume showed moderate positive correlation insert ignore into journalissuearticles values(r=0.365; p<0.001);. No correlation between random blood glucose with PSA or IPSS was found in this study. This study found random blood glucose has positive correlation with prostate volume. We recommend enhancing blood glucose control to prevent the progress of prostate enlargement.
Keywords : blood glucose, prostate, prostate specific antigen, urology

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