An evaluation of the laboratory and clinical data of the Crimean-Congo hemorrhagic fever patients during the COVID-19 pandemic

Authors : Pinar ÖNER, Müge ÖZGÜLER

Pages : 107-112

View : 162 | Download : 140

Publication Date : 2023-03-18

Article Type : Research Paper

Abstract :In this study, the purpose was to investigate the demographic, laboratory, and clinical characteristics of the Crimean-Congo Hemorrhagic Fever insert ignore into journalissuearticles values(CCHF); cases that were treated in our hospital during the Coronavirus disease-2019 insert ignore into journalissuearticles values(COVID-19); pandemic. It was also investigated whether the patients hospitalized with a provisional diagnosis of CCHF who tested negative for CCHF PCR were infected with COVID-19. In our study, data insert ignore into journalissuearticles values(epidemiological, clinical, laboratory, prognosis); from 38 patients diagnosed with CCHF through reverse-transcriptase polymerase chain reaction insert ignore into journalissuearticles values(PCR); and viral-RNA and/or Immunoglobulin M antibodies using ELISA between May 2020 and November 2022 were investigated retrospectively. Of all the patients, 23 were CCHF PCR insert ignore into journalissuearticles values(+); and 15 were CCHF PCR insert ignore into journalissuearticles values(-);.15 insert ignore into journalissuearticles values(65.2%); of PCR insert ignore into journalissuearticles values(+); patients and 9 insert ignore into journalissuearticles values(60%); of PCR insert ignore into journalissuearticles values(-); patients were engaged in farming. 65.2% of PCR insert ignore into journalissuearticles values(+); and 26.7% of PCR insert ignore into journalissuearticles values(-); patients presented with a history of tick bites. 21 insert ignore into journalissuearticles values(91.3%); of PCR insert ignore into journalissuearticles values(+); and 12 insert ignore into journalissuearticles values(80%); of PCR insert ignore into journalissuearticles values(-); patients had a history of rural living. Among the PCR insert ignore into journalissuearticles values(+); patients, 65.2%, 17.4%, and 17.4% received treatment for CCHF in 2022, 2021, and 2020 respectively. 87% of PCR insert ignore into journalissuearticles values(+); and 60% of PCR insert ignore into journalissuearticles values(-); patients were discharged after full recovery. The most common symptoms were fever, diffuse body ache, weakness, and headache. Significant differences were found between PCR insert ignore into journalissuearticles values(+); and PCR insert ignore into journalissuearticles values(-); patients in terms of leukocytes, LDH, INR, NEU, PLT, fibrinogen, and NLR values. 3 patients hospitalized with a provisional diagnosis of CCHF tested negative for CCHF PCR and positive for COVID-19 PCR. Thoracic CT, clinical, and laboratory findings of these patients showed no differences from the other patients. The possibility of misdiagnosis should be considered in CCHF and COVID-19 infections due to their similar symptoms and indications. Extensive multicentric studies need to be conducted to investigate the causes of the increased number of CCHF cases during the pandemic.
Keywords : Crimean Congo Hemorrhagic Fever, Crimean Congo Hemorrhagic Fever, COVID 19, pandemic, tick

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