Investigation of the Relationship between Clinical Severity of Acne and Inflammatory Parameters in Patients with Acne Vulgaris

Authors : Hanife Merve AKÇA, Kevser TUNCER KARA

Pages : 205-210

View : 75 | Download : 88

Publication Date : 2023-07-19

Article Type : Research Paper

Abstract :Objective In this study, we investigated whether the Neutrophil /Lymphosite insert ignore into journalissuearticles values(N/L); ratio, mean platelet volume insert ignore into journalissuearticles values(MPV); value, GADS insert ignore into journalissuearticles values(The global acne rating system); score and other inflammatory parameters are related in acne vulgaris patients. Methods One-hundred acne patients, aged between 18–40 years, who treated at the Karaman Training and Research Hospital Dermatology Polyclinic between January and March 2022 were included in the study. Age, sex, duration of disease, medications and additional systemic diseases were recorded. Acne patients included in the study were tested for N/L ratio, erythrocyte sedimentation rate insert ignore into journalissuearticles values(ESR, mm/hr);, C-reactive protein insert ignore into journalissuearticles values(hsCRP, mg/L);, platelet count insert ignore into journalissuearticles values(PLT/L); and insert ignore into journalissuearticles values(MPV/FL);. GADS scores calculated. Results There was a significant difference in ESR insert ignore into journalissuearticles values(p < 0.001); and CRP levels insert ignore into journalissuearticles values(p = 0.002); in patients with high GADS scores compared to those with low GADS scores .In all patients, the mean GADS score was 24.77 ± 11.00, and GADS scores were positively correlated with ESR and CRP levels. In our binary logistic regression analysis of age, sex, time, N/L ratio, PLT/L, MPV and ESR for identifying risk factors for severe acne vulgaris, the model explained 25.7% of high GADS scores. A high CRP level was identified as a risk factor for having a high GADS score. Conclusion In our study, we evaluated acne patients because it affects many age groups, is common, and sometimes causes extensive inflammation.
Keywords : acne severity, inflammatory parameters, inflammatory diseases, acne vulgaris

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