Need for long-term permanent pacemaker and its association with mortality in patients undergoing transcatheter aortic valve implantation

Authors : Özlem ÖZBEK, Mehmet CAN

Pages : 370-377

View : 76 | Download : 57

Publication Date : 2023-07-19

Article Type : Research Paper

Abstract :Despite two decades of experience and increased procedural success in TAVI, there are still matters of debate concerning need for PPI. We aimed to investigate the frequency of permanent pacemaker implantation insert ignore into journalissuearticles values(PPI); need and the long-term impact of PPI on all-cause mortality in patients with Transcatheter Aortic Valve Implantation insert ignore into journalissuearticles values(TAVI);. All TAVI recipients between June 2016 and January 2021 admitted to our tertiary center were included retrospectively. In-hospital data were retrieved from the institutional digital database and later mortalities were recorded from the national E-Health application. The primary outcome was to determine the frequency of PPI requirement following TAVI. Median follow-up was 52 insert ignore into journalissuearticles values(12-72); months. PPI had been required in 20 insert ignore into journalissuearticles values(15%); of 132 TAVI recipients. PPI was necessary in 25% of Evolut R insert ignore into journalissuearticles values(Medtronic, CA, USA);, 4% of Edwards Sapien insert ignore into journalissuearticles values(Edwards Lifesciences, CA, USA);, 16% of Portico insert ignore into journalissuearticles values(Abbott Structural Heart, St Paul, MN, USA);, 26% of Medtronic CoreValve insert ignore into journalissuearticles values(Medtronic, CA, USA);, 20% of Myval THV insert ignore into journalissuearticles values(Meril Life Sciences, Gujarat, India);, and none of ACURATE neo™ insert ignore into journalissuearticles values(Boston Scientific, Marlborough, MA, USA); recipients. Mortality was similar among those with and without PPI requirement. Multiple regression revealed that hyperlipidemia and preoperative valvuloplasty significantly decreased risk for all-cause mortality, while higher CRP increased the risk of mortality. New generation TAVI devices appear to decrease the frequency of PPI need compared to older generation devices, as reported in the literature. PPI was not associated with all-cause mortality at a median follow-up of 52 months in TAVI recipients.
Keywords : Transcatheter aortic valve replacement, pacemaker, mortality

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