DO PEDIATRIC INDIVIDUALS WITH ADENOID HYPERTROPHY HAVE DEVELOPMENTAL DIFFERENCES IN BRAIN ANATOMICAL STRUCTURES? A RETROSPECTIVE MAGNETIC RESONANCE IMAGING STUDY

Authors : Sefa Işıklar, Dilek Sağlam

Pages : 118-124

Doi:10.52831/kjhs.1778365

View : 46 | Download : 205

Publication Date : 2025-12-30

Article Type : Research Paper

Abstract :Objective: Adenoid hypertrophy (AH) can cause changes in the brain by causing sleep-disordered breathing and obstructive sleep apnea. However, it has not been investigated whether AH affects the brain anatomy as a single factor independent of these diseases. In this study, we investigated the effects of AH on brain development using the estimated brain age (EBA) method. Method: This retrospective study included 55 individuals (39 males) with AH, aged 1-12 years, and 55 individuals of similar age and sex without AH. We used the adenoid-nasopharyngeal ratio (ANR: ratio of adenoid thickness to nasopharynx width) to detect AH. We used volBrain\\\'s BrainStructureAges (BSA) pipeline for EBA on brain anatomical structures. We compared the data with SPSS (ver.28). Results: ANR were higher in AH group (0.66±0.06) than control group (0.40±0.09) (p 0.05). Mean EBA values of cortical and subcortical anatomical regions ranged from 6.51 to 7.97 years in the AH group and from 6.56 to 8.22 years in the control group. There was no statistically significant difference in EBA values of brain regions between AH and control groups (p>0.05). Conclusion: This study showed that mild AH does not negatively affect children\\\'s brain development in terms of EBA. Although minor deviations in EBA were observed in selected cortical and subcortical regions, these variations remained within the normal range of developmental heterogeneity. These findings demonstrated that mild AH is not an independent risk factor for brain development in the pediatric population.
Keywords : Adenoid Hipertrofisi, Yaş Tahmini, Beyin, Pediatri, Manyetik Rezonans Görüntüleme

ORIGINAL ARTICLE URL