Mapping of Gradient Patterns Generated with Helmholtz Coils for Localized Magnetic Fluid Hyperthermia

Authors : Serhat KÜÇÜKDERMENCİ

Pages : 159-166

Doi:10.34088/kojose.792056

View : 20 | Download : 5

Publication Date : 2022-11-30

Article Type : Research Paper

Abstract :Magnetic fluid hyperthermia insert ignore into journalissuearticles values(MFH); is a new generation cancer treatment method under development. One of the challenges that arise in the practical applications of MFH is the limited control of magnetic nanoparticles insert ignore into journalissuearticles values(MNP);. In order to overcome this problem, new approaches are being investigated in MFH tests. Localization of MNP oscillations can be achieved through static magnetic field-free region insert ignore into journalissuearticles values(FFR); and static magnetic field insert ignore into journalissuearticles values(SMF); gradients generated by permanent magnets or electromagnets. In this study, Helmholtz coils were used as SMF source to generate gradient patterns insert ignore into journalissuearticles values(GPs);. Finite element method simulation was used to predict GPs that would emerge in the study area. An experiment platform was produced in which the GP would be generated with parametric current changes. Measurements were taken when source currents were insert ignore into journalissuearticles values(1.1, 1.1 );, insert ignore into journalissuearticles values(2.2, 2.2);, insert ignore into journalissuearticles values(4.4, 4.4); and insert ignore into journalissuearticles values(2.2, -2.2); A, respectively. It was observed that FFR form could be manipulated with coil current. The mapping of the GPs and determining FFRs for the use of localized MFH were discussed for the first time in this study. The findings provide insight into which GP is appropriate in which situations in localized MFH.
Keywords : Cancer Treatments, Field Free Region, Magnetic Fluid Hyperthermia, Helmholtz Coils, Static Magnetic Field