The role of pentavalent tc-99m dmsa in the differential diagnosis for cervical lymphadenopathies

Authors : M DANACI, Ht TUROĞLU, B BOR, Hi EROL, Z ÇANKIR, H TOR, F KARSLI

Pages : 73-78

View : 14 | Download : 12

Publication Date : 1995-03-01

Article Type : Research Paper

Abstract :Twenty patients with palpable cervical lymphadenopathy underwent Tc-99m insert ignore into journalissuearticles values(V); DMSA scintigraphy during their diagnostic work-up. In this prospective study, the scintigraphic findings were correlated with the clinical diagnoses and the results of the routine laboratory tests insert ignore into journalissuearticles values(complete blood count, biochemical analyses, chest X-ray, and tuberculin skin tests); and histopathological examinations of the excisional biopsy specimens. In patients with tuberculous lymphadenitis insert ignore into journalissuearticles values(diagnosed clinically and histopathologically); the intense Tc-99m insert ignore into journalissuearticles values(V); DMSA uptake in the involved cervical lymph nodes was found to be significant. In seems thaï Tc-99m insert ignore into journalissuearticles values(V); DMSA scintigraphy is a safe and non-invasive diagnostic imaging modality, that may be utilized in the initial work-up to assist in the differential diagnosis of cervical lymphadenopathies. The observed affinity of the radiopharmaceutical for mycobacteria-infected cervical lymph nodes seems to be congruent with the localization mechanism insert ignore into journalissuearticles values(i.e. structural similarity to phosphate ion); proposed by Ohta and his coworkers.
Keywords : Cervical lymphadenopathy, tuberculous lymphadenitis, mycobacterial lymphadenitis, Tc 99m V, DMSA scintigraphy