Effect of gestational diabetes and smoking on the elemental status of the maternal fetal placental unit

Authors : C ÇOKER, H AYDIN, N AŞKAR, B ERSÖZ, F AKERCAN

Pages : 129-135

View : 46 | Download : 17

Publication Date : 1996-06-01

Article Type : Research Paper

Abstract :Objective: This study is undertaken to investigate the effects of gestational diabetes and smoking on the elemental status of the maternal-fetal-placental unit. Methods: Concentrations of Cu, Zn, Fe, Mg and Ca are determined in placental tissue, maternal and fetal plasma and fetal red blood cell samples obtained during delivery insert ignore into journalissuearticles values(group 1 gestational diabetes, n=8; group 2 smoking, n=8; group 3 healthy controls, n=9);. The elemental analysis is performed by inductively coupled atomic emission spectrophotometry. Results: The diabetes group shows no significant differences with respect to the elemental status of maternal and fetal plasma and fetal red blood cells. The only significant variation is observed in placental Fe insert ignore into journalissuearticles values(p<0.05);. In the smoking group, significant decreases are determined in placental Ca insert ignore into journalissuearticles values(p<0.05);, matermal plasma Zn, Mg and Ca insert ignore into journalissuearticles values(p<0.05);, along with fetal plasma Mg insert ignore into journalissuearticles values(p<0.01); and Ca insert ignore into journalissuearticles values(p<0.05); levels. Conclusion: The results are indicative of variations in perinatal elemental metabolism in abnormal states of pregnancy, especially smoking, however the mechanisms underlying these alterations are yet to be elucidated.
Keywords : Trace elements, electrolytes, pregnancy, gestational diabetes, smoking

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