HOMOCYSTEINE IS NOT AN INDICATOR OF RESTENOSIS RISK AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY

Authors : Önder SİRİKCİ, Vedat AYTEKİN, Güler TOPÇU, Saide AYTEKİN, Cemsid DEMİROĞLU, Cem`i DEMİROĞLU

Pages : 137-142

View : 23 | Download : 8

Publication Date : 2016-12-03

Article Type : Research Paper

Abstract :Objective: Elevated homocysteine levels have been associated with increased risk of atherosclerotic vascular disease. The possible association of homocysteine with restenosis after percutaneous transluminal coronary angioplasty insert ignore into journalissuearticles values(PTCA); has not been widely investigated. Methods: In order to determine if a relationship exists between serum homocysteine levels and restenosis after PTCA, serum homocysteine level were determined in 204 patients who underwent a successful PTCA procedure and stant implantation. The patients were followed with clinical examinations and exercise tests at 1, 3, and 6 months, and a control coronary angiography was performed after 6 months to evaluate restenosis. Homocysteine levels were determined with fluorescence polarization immunoassay. Results: Of the 146 patients who underwent angiographic evaluation, 57 insert ignore into journalissuearticles values(39 %); had restenosis, whereas 89 insert ignore into journalissuearticles values(61 %); did not. The homocysteine distributions were compared in these two groups of patients. Although the average homocysteine levels were higher in the restenosed group, the difference was not statistically significant. Conclusion: Because of its wide distribution, serum homocysteine values do not seem to be a useful indicator for the risk of restenosis after PTCA. Key Words: Homocysteine, Restenosis, PTCA
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