PREDICTION OF INSIGNIFICANT PROSTATE CANCER IN MEN WITH STAGE T1C DISEASE

Authors : Kamil Çam, Levent Türkeri, Atıf Akdaş

Pages : 59-63

View : 16 | Download : 6

Publication Date : 2016-12-03

Article Type : Research Paper

Abstract :Objective: In this retrospective study, we evaluated the ability of preoperative parameters to predict tumor significance in men with stage T1c disease who underwent radical retropubic prostatectomy. Patients and Methods: A total of 26 consecutive patients who underwent radical retropubic prostatectomy owing to clinically localized disease fulfilled the criteria for insignificant cancer namely PSA density lower or equal to 0.10, presence of Gleason grade <4 insert ignore into journalissuearticles values(Gleason sum <6);, number of cores insert ignore into journalissuearticles values(<3); involved with cancer, and tumor percentage less than 50% for insignificant prostate cancer. Additionally, we only included the patients with a PSA level of less than 10 ng/ml. Results: According to pathological examination, 6 insert ignore into journalissuearticles values(23%); of these patients had bilateral insert ignore into journalissuearticles values(pT2c); disease, 5 insert ignore into journalissuearticles values(19.2%); had extracapsular disease insert ignore into journalissuearticles values(pT3a-b);, 2 insert ignore into journalissuearticles values(7.7%); had seminal vesicle insert ignore into journalissuearticles values(pT3c); involvement and 2 insert ignore into journalissuearticles values(7.7%); had positive surgical margins. Consequently, at least 50% of these cases were significant cancer. Conclusion: In conclusion, our data demonstrated that the patient and the physician must be aware of the variability and insufficiency of these preoperative algorithms for predicting insignificant cancers in discussing treatment alternatives. Key Words: Prostate cancer, Stage T1c disease, Insignificant tumor.
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