The natural course of gastric intestinal metaplasia in Turkish Patients: A single-center observational cohort study

Authors : Coskun Ozer DEMIRTAS, Mesut KOLDAS, Metehan YILMAZ, Muhammed Zahid SAHIN, Muhammed Talha SOYKUVVET, Cigdem ATAIZI CELIKEL, Feyza GUNDUZ

Pages : 229-233

Doi:10.5472/marumj.1013580

View : 33 | Download : 9

Publication Date : 2021-10-27

Article Type : Research Paper

Abstract :Objective: Gastric intestinal metaplasia insert ignore into journalissuearticles values(GIM); is considered as a predisposing lesion for the development of gastric cancer and is recommended to be kept under surveillance in designated intervals. We aimed to assess the natural course of GIM in a large Turkish cohort. Materials and Methods: We retrospectively reviewed findings from pathology reports of gastric biopsies conducted between 2011 to 2018 to reveal patients diagnosed with solitary GIM in their index pathology report. Progression of GIM was pre-defined as; lowgrade dysplasia insert ignore into journalissuearticles values(LGD);, high-grade dysplasia insert ignore into journalissuearticles values(HGD);, or gastric malignancy. Results: The median follow-up period of the study population was 34 insert ignore into journalissuearticles values(12-128); months. Out of 109 patients with GIM at the entry, 54 insert ignore into journalissuearticles values(49.6%); patients had stable GIM, whereas 53 insert ignore into journalissuearticles values(48.6%); cases had no signs of GIM at their final endoscopy. Only two insert ignore into journalissuearticles values(1.8%); patients progressed to LGD, but no HGD or malignancy was detected in the follow-up. Conclusion: Although, considered as a premalignant lesion and offered surveillance globally, progression of GIM was very low in a large Turkish cohort. Further prospective studies in larger cohorts are required to enlighten the obscure strategies in the surveillance of gastric malignancy.
Keywords : Gastric intestinal metaplasia, Gastric cancer, Dysplasia, Surveillance