Investigation of Thyroid Hormones and Prolactin Levels in Fertile and Infertile Women

Authors : Arzu Şahin, Feyyaz Önder

Pages : 1-6

Doi:10.19127/mbsjohs.63680

View : 29 | Download : 15

Publication Date : 2016-04-27

Article Type : Research Paper

Abstract :Objective: This study was conducted to investigate thyroid hormones and prolactin levels in fertile and infertile women. Materials and Methods: The study enrolled a total of 84 women, 40 infertile and 44 fertile, aged between 15-45 years and applied to Kars Maternity and Child Hospital, Obstetrics Clinic and Artvin State Hospital, Obstetrics and Gynecology Clinic. The study population was divided into 3 groups: Group P insert ignore into journalissuearticles values(n=30, women having primary infertility);, Group S insert ignore into journalissuearticles values(n=10, women having secondary infertility); and Group F insert ignore into journalissuearticles values(N=44, fertile women);. Blood samples were obtained in early follicular phase and serum thyrotropin insert ignore into journalissuearticles values(TSH);, free triiodothyronine insert ignore into journalissuearticles values(FT 3); , free thyroxine insert ignore into journalissuearticles values(FT 4 ); and prolactin levels were determined by Microparticle Enzyme Immunoasay insert ignore into journalissuearticles values(MEIA); method. Results: Serum TSH levels were 1.70±0.40, 1.60±0.20 and 0.80±0.20 µIU/ml for the groups F, P and S, respectively insert ignore into journalissuearticles values(p> 0.05);.  FT 3 levels were 2.36±0.06, 2.46±0.09 and 2.35±0.2 pg/ml while FT 4 levels were 0.98±0.02, 0.94±0.04 and 1.00±0.03 ng/dl for the groups F, P and S, respectively. There was a significant negative correlation between TSH and FT 4 insert ignore into journalissuearticles values(p=0.012, r = -0.275); and a significant positive correlation between FT 3 and FT 4 insert ignore into journalissuearticles values(p=0.002, r = 0.330);. Serum prolactin levels were measured as 16.70±2.60, 21.10± 2.10 and 16.00±1.90 ng/ml respectively for the groups F, P and S and no significant difference was detected between the groups with respect to prolactin levels insert ignore into journalissuearticles values(p >0.05);. Conclusion: As a result, there was no difference between the groups in terms of TSH, FT 3 , FT 4 and prolactin levels. Hormone levels were generally within normal limits and therefore we determine no significant relationship between infertility and investigated parameters in this study.
Keywords : TSH, FT3, FT4, Prolactin, Infertility, Fertilty