The Relationship Among Helicobacter pylori Positivity, Acute Phase Reactants, Blood Groups and Tumor Markers in Urea Breathe Test

Authors : Ali Şenkaynağı, Mustafa Yıldız

Pages : 13-19

Doi:10.19127/mbsjohs.307150

View : 25 | Download : 9

Publication Date : 2017-08-28

Article Type : Research Paper

Abstract :Objective: In this study, positivity of Helicobacter pylori which is very common health problem for human, was examined by C 14 urine breath test and in this group also blood samples, acute phase reactants, tumor markers were examined for the specific correlation Methods: Blood samples of 130 patients which was examined by C 14 urine breath test, were drawn. In order to perform the urea breath test, which was the basis of our study, the patient was starved for at least 6 hours before the test and did not use antibiotics 1 month before and active acid inhibitors 1 week before. Following a 6-hour hunger period, 37 kBg of 14 C-urea capsules 50 mL water were given. Breath samples were collected at 10 minutes with a dry cartridge system insert ignore into journalissuearticles values(BREATHCARD);.  In this group also blood samples, acute phase reactants insert ignore into journalissuearticles values(crp, aso, sedim, rf);, tumor markers insert ignore into journalissuearticles values(CEA, CA 19-9, CA 15-3); were examined for the specific correlation. Results: Test results for 57 of 130 patients were found to be positive insert ignore into journalissuearticles values(43.84%); while it was found to be negative insert ignore into journalissuearticles values(56.16%); in 73 patients. Reference ranges for blood parameters were 13.6-17.2 for HGB, 39.5-50.3 for HCT, 5.2-12.4 for WBC, 0-200 for ASO, 3.02 for CRP, 0-15 for RF, 0-3 for CEA, 0-35 for CA 19-9, 0-31.3 for CA 15-3 The mean age of patients with negative H. pylori infection was 39.41 and the positive was 39.03. 35 of the 57 H. pylori positive patients in the total 130 patients were female insert ignore into journalissuearticles values(61.4%);, 22 were male insert ignore into journalissuearticles values(38.6%);; Of 73 negative patients, 44 were female insert ignore into journalissuearticles values(60.3%); and 29 were male insert ignore into journalissuearticles values(39.7%);. There was no sex-related collagen of H. pylori . 22 persons insert ignore into journalissuearticles values(38.6%); of the positive H. pylori blood group were found in the blood group A, 9 insert ignore into journalissuearticles values(15.8%); were in the blood group B, 11 insert ignore into journalissuearticles values(19.3%); were in the group AB and 15 insert ignore into journalissuearticles values(26.3%); were in the group O. It was observed that 21 patients insert ignore into journalissuearticles values(28.8%); in negatives of H. pylori were blood group A, 17 patients insert ignore into journalissuearticles values(23.3%); were blood group B, 14 patients insert ignore into journalissuearticles values(19.2%); were blood group AB and 21 patients insert ignore into journalissuearticles values(28.8%); were group O.  No significant difference was observed between blood groups and H. pylori infection with Rh factor, and no linkage was detected. Conclusion: As a result, there were no significant correlation were found between acute phase reactants, tumor markers and ABO/ Rh blood groups for H. pylori positives.
Keywords : H pylori, C 14 urea breath test, tumor markers, acute phase reactants, blood groups