A Case of Recurrent Granulomatous Disease

Authors : Emine Serap YILMAZ

Pages : 296-300

Doi:10.19127/mbsjohs.936171

View : 23 | Download : 10

Publication Date : 2021-08-31

Article Type : Other Papers

Abstract :Chronic granulomatous disease insert ignore into journalissuearticles values(CGD); is an extremely rare genetically heterogeneous disorder characterized by serious life-threatening infections. CGD is caused by a defect of the nicotinamide adenine dinucleotide phosphate insert ignore into journalissuearticles values(NADPH); oxidase system. The disease is characterized by increased inflammation and granuloma formation secondary to recurrent infections. CGD typically involves the lungs, liver, and lymph nodes. Most patients with CGD are diagnosed in childhood. In this case report, we aimed to present a patient with recurrent granulomatous diseases who could not be diagnosed despite reaching adulthood. A nineteen-year-old male patient who was previously diagnosed with granulomatous inflammation and lymphadenopathy and had consanguineous parents was examined for persistent fever and cough and diagnosed with chronic granulomatous disease. This case is presented to show that in countries where consanguineous marriage is common, this genetic disorder can also be diagnosed in adulthood.
Keywords : Fever, Genetic Disorders, Granuloma, Lymphadenopathy, Pneumonia