Synthesis and Characterization of Oleic Acid Coated Magnetic Nanoparticles for Hyperthermia Applications

Authors : Fatih SENTURK, Soner CAKMAK, Goknur GULER OZTURK

Pages : 16-29

Doi:10.38061/idunas.657975

View : 58 | Download : 16

Publication Date : 2019-12-31

Article Type : Research Paper

Abstract :In this study, we aimed to synthesize stable dispersions of iron oxide nanoparticles insert ignore into journalissuearticles values(IONs); coated with different amounts of oleic acid insert ignore into journalissuearticles values(OA); suitable for magnetic nano hyperthermia applications. For this purpose, bare and different amounts of oleic acid insert ignore into journalissuearticles values(0.2%, 0.5% and 1.0%, v/v); coated IONs were prepared by co-precipitation method. Then, their structures, morphologies, magnetic properties and heating abilities were characterized by using suitable techniques. IONs+1.0%OA nanoparticles showed low agglomeration with high dispersion capacity. Moreover, 1.0% OA coating showed the highest heating ability with a temperature increase of insert ignore into journalissuearticles values(25.2 °C); compared to IONs+OA insert ignore into journalissuearticles values(0.2%, 16.4 °C; 0.5%, 19 °C);, but similar with bare IONs insert ignore into journalissuearticles values(26.7 °C);. The specific absorption rate insert ignore into journalissuearticles values(SAR); values of bare IONs and IONs+OA insert ignore into journalissuearticles values(0.2%, 0.5%, 1.0% v/v); were found as 39.50, 34.81, 23.36 and 45.98 W/g, respectively. Our results showed that the comparable hyperthermia effect of IONs+1.0%OA with bare IONs was attributable to their uniform dispersion performance along with higher SAR values. We concluded that the dispersion of hydrophobic IONs+OA in an aqueous medium is one of the critical requirements for increasing temperature in magnetic nano hyperthermia applications.
Keywords : Iron oxide nanoparticles, magnetic hyperthermia, oleic acid coated, co precipitation

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