Remineralization Potential of Ginger-Honey on Initial Enamel Lesions of Different Depth

Authors : Esma Turkmen, Dilek Tağtekin, Zeynep Ceren Çelik, Funda Yanıkoğlu

Pages : 80-87

Doi:10.15311/selcukdentj.1499934

View : 53 | Download : 64

Publication Date : 2025-04-21

Article Type : Research Paper

Abstract :Aim: The present study aims to determine the remineralization efficacy of toothpaste with the active ingredients of ginger and honey on in-vitro produced early dental caries lesions by using ultrasound, fluorescence, surface microhardness and light and scanning electron microscope methods. Methods: Total of 105 enamel samplesin total were divided into three main groups which were exposed to a demineralizing solution for 18 (D1), 36 (D2), and 72 (D3) hours to take initial measurements by ultrasound, fluorescence, and surface microhardness, SEM. All main groups were divided into three subgroups each then, topically applied a toothpaste with NaF content (R1N) and a dental toothpaste with ginger-honey content (R1G) (Gumgumix) by a toothbrush three times a day for five minutes and stored in remineralizing solution, measured at the end. The one-way ANOVA test was used to compare the continuous data. Results: Toothpaste with ginger-honey content produced significant remineralization results (p=0.033) on the 52-micron initial enamel lesions (D1) by microhardness. Similarly, the fluorescence size (p=0.001), microscope (p<0.001) and microhardness (p=0.001) results of the 80-micron lesion distinctly showed remineralization. In the 140-micron lesions (D3), the FluoreCam, microscope, and microhardness marked some changes on demineralization while the ultrasound detected the changes on both the demineralization and remineralization (p=0.035, p=0.025). When the remineralization and demineralization variations were compared, the ultrasound method, along with the microhardness, control, method, appeared to be the only method that differed in all groups in general. In addition, the dental toothpaste with ginger-honey content produced the highest remineralization values. Conclusion: As a result, the application of the dental toothpaste with ginger-honey content produced higher remineralization effect in all demineralization groups than the NaF toothpaste. Keywords: Initial enamel lesion, Ginger, remineralization, ultrasound, Fluoresence.
Keywords : Başlangıç mine lezyonu, Zencefil, remineralizasyon, ultrason, FluoreCam.