Epidemiologic, clinical findings and risk factors of recurrent herpes labialis in healthy adult patients: a case-control study

Authors : Mohammad Nassaji, Raheb Ghorbani, Ramin Taheri, Maryam AZİZZADEH, Fatemeh ABBASSYAN

Pages : 545-549

Doi:10.18621/eurj.384806

View : 16 | Download : 13

Publication Date : 2019-05-04

Article Type : Research Paper

Abstract :Objectives: Herpes labialis is a common viral infection and characterized by recurrent vesicular lesion primarily on the lips and perioral skin. The aim of this study was to determine the epidemiological, clinical characteristics and trigger factors associated with r ecurrence herpes labialis in adult patients . Methods: This case-control study was conducted with the participation of one hundred adult patients and the same number of control. Data collected about demographics, clinical, as well as trigger factors from individuals who met inclusion criteria. Results: Seventy-four percent of cases and 34% of controls were female that showed significant difference insert ignore into journalissuearticles values( p < 0.001);. Mean body mass index of patients was significantly higher than controls insert ignore into journalissuearticles values( 25.9 ± 2.9 kg/m 2 versus 22.0 ± 2.9 kg/m 2 , p < 0.001);. The most common location of the lesions during the last episode of infection was upper lip insert ignore into journalissuearticles values(65%); . The number of lesions was single in 58% and multiple in 42% of patients. The frequency of episodes per year was more than two attacks each year in most patients insert ignore into journalissuearticles values(83%);. Positive family history of r ecurrence herpes labialis was found in 50% and 20% of cases and controls respectively insert ignore into journalissuearticles values( p < 0.001);. Emotional stress insert ignore into journalissuearticles values(61%);, sunlight exposure insert ignore into journalissuearticles values(54%); and flu insert ignore into journalissuearticles values(37%); were the main triggering factors reported by the patients. Conclusions: This study revealed that r ecurrence herpes labialis is more common in women and on the upper lip. Family history of r ecurrence herpes labialis was positive significantly in patients. The most common trigger factors were stress, sunlight exposure, flu. Higher body mass index was a probable risk factors for r ecurrence herpes labialis . 
Keywords : Recurrence herpes labialis, adult, epidemiology, trigger factors