The prognostic role of Charlson comorbidity index for critically ill elderly patients

Authors : Abdulkerim YILDIZ, Ali YİĞT, Ali Ramazan BENLİ

Pages : 67-72

Doi:10.18621/eurj.451391

View : 39 | Download : 6

Publication Date : 2020-01-04

Article Type : Research Paper

Abstract :Objectives: Comorbidities represent a risk factor for adverse events in several critical illnesses. The aim of this study was to identify the relationship between the Charlson Comorbidity Index insert ignore into journalissuearticles values(CCI); with mortality and length of stay insert ignore into journalissuearticles values(LOS); in critically ill elderly patients. Methods: A retrospective analysis was made of patients admitted to our tertiary adult intensive care unit insert ignore into journalissuearticles values(ICU); between January 2015 and January 2016. The impact of comorbidity was evaluated with the CCI. Other required data were retrieved from the patients` follow-up records. Results: The study included a total of 251 patients. The mean age was 78.79 ± 6.70 years. The total mortality rate was 41.0%. The most common cause for admission was sepsis and acute respiratory failure insert ignore into journalissuearticles values(18.3% vs 18.3%);. The median APACHE II score was significantly higher in non-survivors than survivors insert ignore into journalissuearticles values(31.0 [13.0-47.0] vs 21.0 [9.0-40.0]; p < 0.01);. The median CCI was 2.0 insert ignore into journalissuearticles values(0.0-7.0); for survivors and 3.0 insert ignore into journalissuearticles values(1.0-10.0); for non-survivors. The CCI of non-survivors was significantly higher than that of survivors insert ignore into journalissuearticles values( p = 0.005);. Patients with CCI > 3 had higher mortality than those with CCI ≤ 3 insert ignore into journalissuearticles values( p < 0.05);. The odds ratio of the APACHE II score for mortality was 1.214 insert ignore into journalissuearticles values(95% CI: 1.154-1.276);, and for CCI it was 1.320 insert ignore into journalissuearticles values(95% CI: 1.088-1.602);. There was a significant positive correlation between CCI and LOS insert ignore into journalissuearticles values(r=0.147; p = 0.020);. Conclusions: CCI is strongly associated with both mortality and LOS. It can be used as a prognostic marker for elderly patients in critical care. 
Keywords : Charlson comorbidity index, older patients, critically ill, mortality

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