Red cell distribution width and red cell distribution width to total serum calcium ratio as predictors of mortality in acute pancreatitis: a retrospective cohort study

Authors : Cihan BEDEL, Sefa TÜRKOĞLU

Pages : 92-98

Doi:10.18621/eurj.465878

View : 19 | Download : 8

Publication Date : 2020-03-04

Article Type : Research Paper

Abstract :Objectives: We investigated whether red cell distribution width insert ignore into journalissuearticles values(RDW); and red cell distribution width to total serum calcium insert ignore into journalissuearticles values(RDW-to-TSC); ratio were associated with mortality in patients with acute pancreatitis insert ignore into journalissuearticles values(AP);. Methods: A total of 170 patients who present emergency department   between January 2017 and June 2018 with a diagnosis of AP were enrolled in this study. A comparison between survivor and nonsurvivor AP patients was performed. Diagnosis of AP were defined according to the revised Atlanta classification 2012. Variables evaluated included demographics, hospital stay, laboratorial parameters and mortality . Results: AP related in-hospital mortality was 6.4%. Red cell distribution insert ignore into journalissuearticles values(RDW);, white blood cell insert ignore into journalissuearticles values(WBC);, platelet, serum glucose and RDW-to-TSC ratio were associated with AP mortality. RDW-to-TSC ratio had the highest AUC insert ignore into journalissuearticles values(0.88; 95% CI, 0.756-1.0);, followed by RDW, serum glucose, platelet and WBC insert ignore into journalissuearticles values(AUC = 0.801, 0.797, 0.743 and 0.687 respectively);. A cut-off value of RDW-to-TSC ratio >2.0, the highest sensitivity insert ignore into journalissuearticles values(91.9%);, specificity insert ignore into journalissuearticles values(81.1%);, PPV insert ignore into journalissuearticles values(82.9%);, and NPV insert ignore into journalissuearticles values(91.1%); were achieved for prediction of AP related in-hospital mortality in approximately 86.5% of the cases insert ignore into journalissuearticles values( p < 0.001);. Conclusions: RDW and TSC are   simple, inexpensive routine serum parameters, provided in a complete blood count test and available at admission. This study showed that RDW > 16.6 and RDW-to-TSC > 2.0 were very good predictors for AP mortality. 
Keywords : acute pancreatitis, mortality, red cell distribution width, serum calcium