The relationship between postoperative atrial fibrillation after coronary artery bypass surgery and inflammation

Authors : Burak ERDOLU, Ahmet Kağan AS

Pages : 409-415

Doi:10.18621/eurj.683034

View : 46 | Download : 12

Publication Date : 2020-09-04

Article Type : Research Paper

Abstract :Objectives: Postoperative atrial fibrillation insert ignore into journalissuearticles values(PoAF); may occur up to 50% after coronary artery bypass grafting insert ignore into journalissuearticles values(CABG); operations. The most important problems related to this are prolonged hospitalizations, thromboembolic cerebrovascular events and new onset heart failure. In this study, we aimed to investigate the relation of high sensitivity C-reactive protein insert ignore into journalissuearticles values(hsCRP); and heat shock protein 70 insert ignore into journalissuearticles values(HSP70); levels and occurrence of PoAF in patients undergoing isolated CABG. Methods: Patients who underwent elective isolated coronary artery bypass surgery between November 2008 and April 2009 in the Cardiovascular Surgery Clinic of Dıskapı Yıldırım Beyazıt Training and Research Hospital were prospectively included in the study. Results: A total of 40 patients insert ignore into journalissuearticles values(20 Off-pump CABG insert ignore into journalissuearticles values(OPCABG);, mean age: 59.3 ± 5.56 years); and 20 On-pump CABG insert ignore into journalissuearticles values(mean age: 60.7 ± 5.3 years);); were included in the study. PoAF ratio was 25% in on-pump CABG patients and 15% in OPCABG group insert ignore into journalissuearticles values( p = 0.356);. Age and diameters of the heart cavities were statistically significantly higher in patients with POAF in both surgical groups. Left ventricular ejection fraction was significantly lower in patients with PoAF. Preoperative hsCRP, postoperative hsCRP, preoperative HSP70 and postoperative HSP70 levels were significantly higher in patients with PoAF who underwent OPCABG insert ignore into journalissuearticles values( p = 0.018, p = 0.044, p < 0.001 and p = 0.047; respectively);. Conclusions: As a result, PoAF is undesirable for CABG operations. PoAF can be predicted by evaluating HSP70 and hsCRP values before coronary bypass operations. 
Keywords : Coronary artery bypass grafting, postoperative atrial fibrillation, inflammation, heat shock protein 70

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