- The European Research Journal
- Volume:8 Issue:2
- Effects of subclinical hypothyroidism on maternal and obstetric outcomes during pregnancy
Effects of subclinical hypothyroidism on maternal and obstetric outcomes during pregnancy
Authors : Simten GENÇ, Başak CINGILLIOĞLU
Pages : 247-255
Doi:10.18621/eurj.1010682
View : 49 | Download : 6
Publication Date : 2022-03-04
Article Type : Research Paper
Abstract :Objectives: Subclinical hypothyroidism has been defined as normal free thyroxine insert ignore into journalissuearticles values(FT4); with elevated thyroid stimulating hormone insert ignore into journalissuearticles values(TSH); levels. The aim of this study is to examine the relationship between the first trimester subclinical hypothyroidism with adverse obstetric outcomes in pregnant women. Methods: This retrospective cohort study was conducted by examining the pregnant women who applied to the Gynecology Department of Okmeydani Training and Research Hospital at their 6th to 14th gestational weeks and had antenatal follow-ups between February 1, 2017 and December 31, 2020. Results: Fetal weight insert ignore into journalissuearticles values(OR: 1; 95% CI, 0.99-1.03, p = 0.023);, gestational age at delivery insert ignore into journalissuearticles values(OR: 0.91; 95% CI, 0.83-0.99, p = 0.022);, and preterm delivery insert ignore into journalissuearticles values(OR: 0.79; 95% CI, 0.48-1.06, p = 0.005); were found to be statistically significant parameters in univariate risk analyses performed in the group whith patients normal T4 levels and TSH levels ≥ 2.5-4 mIU/L. Lower gestational age at delivery insert ignore into journalissuearticles values(OR: 1; 95% CI, 0.93-1.88, p = 0.016);, and higher preterm delivery rates insert ignore into journalissuearticles values(OR: 0.99; 95% CI, 0.96-1.01, p = 0.003); were found to be statistically significant in multivariate risk analysis. Conclusions: The rate of preterm delivery was statistically higher, and fetal weight and week of delivery were significantly lower in the group of pregnant women diagnosed with SCH having TSH values between 2.5 and 4 mIU/L.Keywords : Pregnancy, Preterm birth, Subclinical hypothyroidism
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