Understanding the paradigma of opportunistic screening

Authors : Nilgün GÜLDOĞAN, İlke DALDAL, Aykut SOYDER, Ebru YILMAZ, Aydan ARSLAN

Pages : 598-605

Doi:10.18621/eurj.1033431

View : 16 | Download : 18

Publication Date : 2022-09-04

Article Type : Research Paper

Abstract :Objectives: To provide demographical and pathological characteristics of breast cancer patients diagnosed in a tertiary clinic with opportunistic screening and diagnostic workup and compare the results with the available national and global breast cancer statistics.  Methods: Clinical and pathological data of breast cancer patients diagnosed in our tertiary breast clinic between March 14, 2017 and February 28, 2020 have been entered into a database and analyzed retrospectively. Results were analyzed and compared with the national and global statistics.  Results: The total number of patients included in this study were 137 and the number of tumors was 145. Sixty-four insert ignore into journalissuearticles values(46.7%); patients were detected in screening. All of the patients were female. The mean age was 51.8 years. Eighteen insert ignore into journalissuearticles values(13.1%); patients were young females insert ignore into journalissuearticles values(< 40 years);, 55 insert ignore into journalissuearticles values(40.1%); were in 40-49 years, 26 insert ignore into journalissuearticles values(18.9%); in 50-59 years, 24 insert ignore into journalissuearticles values(17.5%); in > 60-69 years, 14 insert ignore into journalissuearticles values(10.2%); in > 70 years. Of the invasive cancers, 100 insert ignore into journalissuearticles values(79.4%); were invasive ductal, 15 insert ignore into journalissuearticles values(11.9%); invasive lobular, 6 insert ignore into journalissuearticles values(4.8%); pleomorphic lobular, 4 insert ignore into journalissuearticles values(3.2%); papillary, and 1 insert ignore into journalissuearticles values(0.8%); tubular cancer. Distribution of stages were: 13.1% stage 0, 38.6% stage I, 29.6% stage II, 10.3% stage III, and 8.2% stage IV. The mean tumor diameter was 26.6 mm. Estrogen receptor insert ignore into journalissuearticles values(ER);, progesterone receptor insert ignore into journalissuearticles values(PR); and human epidermal growth factor receptor-2 insert ignore into journalissuearticles values(HER-2); were positive in 82.5%, 61.9% and 15.8% of the tumors respectively.  Conclusions: Results of this study are in accordance with the latest results of the National Breast cancer database, a project governed by the Turkish Federation of Breast Disease Societies insert ignore into journalissuearticles values(TMHDF);, considering the tumor size, age distribution, histologic subtype analysis, receptor status. However, the percentage of early-stage tumors was higher in this study.
Keywords : Breast cancer, histology, stages, molecular subtypes, opportunistic screening