The relationship between epicardial fat volume and myocardial perfusion scintigraphy findings

Authors : Süleyman ÖNCÜ, Seyit Ahmet ERTÜRK

Pages : 630-636

Doi:10.18621/eurj.1084333

View : 134 | Download : 156

Publication Date : 2023-07-04

Article Type : Research Paper

Abstract :Objectives: We investigated the epicardial fat volume insert ignore into journalissuearticles values(EFV); between patients with normal perfusion and reversible perfusion abnormalities in the myocardial perfusion scintigraphy insert ignore into journalissuearticles values(MPS); in patients with suspected coronary artery disease insert ignore into journalissuearticles values(CAD);. In addition, we aimed to investigate the relationship of automated analysis parameters obtained in the MPS SPECT examination with EFV. Methods: A total of 295 patients insert ignore into journalissuearticles values(182 F, 113 M); who underwent MPS in our unit with the suspicion of CAD in the last 1 year and who had a recent thorax CT examination were included. EFV measurement in CT scans was done with Invesalius software. MPS was performed in all patients with a one-day stress and rest imaging protocol. In the stress study, imaging was performed approximately 30-45 minutes after intravenous injection of ~12 mCi Tc99m Sestamibi. Rest study imaging was performed approximately 30-60 minutes after intravenous injection of ~25 mCi Tc99m Sestamibi. Results: Median EFV was 53.00 ml insert ignore into journalissuearticles values(interquartile range: 23 ml, range 17-238 ml); in patients with normal MPS, and 62.00 ml in patients with myocardial ischemia on scintigraphy insert ignore into journalissuearticles values(interquartile range: 53 ml, range: 25-207 ml);. The EFV value was statistically significantly higher in patients with reversible ischemia on MPS compared to patients with normal scintigraphy findings insert ignore into journalissuearticles values( p < 0.001);. There was a statistically significant, low, and positive correlation between EFV and summed difference score insert ignore into journalissuearticles values(SDS); values insert ignore into journalissuearticles values( p = 0.002, r = 0.178);. Conclusions: The EFV value was significantly higher in patients with reversible ischemia on MPS compared to patients with normal scintigraphy findings. Also there was a statistically low and positive correlation between EFV and SDS values. The automatic calculation of the EFV value during this examination may be a good additional parameter to detect the presence of ischemia.
Keywords : Epicardial fat volume, Tc 99m MIBI, scintigraphy, summed difference score