Evaluation of umbilical cord blood hematological parameters in pregnant women with fetal growth restriction

Authors : Mustafa Bertan DEMİR, Mehmet AK, Şeyma DAĞLITUNCEZDİ ÇAM, Cevat Rifat CÜNDÜBEY

Pages : 817-822

Doi:10.18621/eurj.1265286

View : 67 | Download : 30

Publication Date : 2023-07-04

Article Type : Research Paper

Abstract :Objectives: The present study attempted to evaluate the relationship between fetal growth restriction insert ignore into journalissuearticles values(FGR); and the platelet-to-lymphocyte ratio insert ignore into journalissuearticles values(PLR); and neutrophil-to-lymphocyte ratio insert ignore into journalissuearticles values(NLR); in singleton term pregnancy. Methods: We carried out this prospective, case-control study at a Training and Research Hospital in Türkiye between May 2021 and January 2023. We utilized ultrasonography to assess singleton pregnancy with FGR between 37-40 weeks of gestation and considered the patients’ last menstrual periods insert ignore into journalissuearticles values(LMD);. Results: We recruited 250 pregnant women in the study and divided them into the FGR insert ignore into journalissuearticles values(n = 125); and healthy control insert ignore into journalissuearticles values(n = 125); groups. Our findings revealed no significant difference between the groups by age, body mass index insert ignore into journalissuearticles values(BMI);, stillbirth history, abortion, tobacco use, and regular pregnancy monitoring insert ignore into journalissuearticles values( p > 0.05);. Fetal birth weights and hospitalization in the neonatal intensive care unit insert ignore into journalissuearticles values(NICU); were also similar between the groups. Yet, 1- and 5-minute APGAR scores were significantly lower in the FGR group than in the control group. In addition, compared to the healthy subjects, the FGR group had significantly increased white blood cell, lymphocyte, neutrophil, platelet counts and NLR and PLR values, but mean platelet volume insert ignore into journalissuearticles values(MPV); remained similar. Conclusions: In a nutshell, our findings suggested that two noteworthy inflammatory markers, NLR and PLR, are likely to elevate in the presence of FGR.
Keywords : Fetal growth restriction, neutrophil to lymphocyte ratio NLR, platelet to lymphocyte ratio PLR, hematologic parameters, cord blood