Long-term outcomes of COVID-19 infection in patients with solid tumors

Authors : Oktay ÜNSAL, Ozan YAZICI, Ömer Faruk ÖZKAN, Gözde SAVAŞ, Nuriye YILDIRIM ÖZDEMİR, Aytuğ ÜNER, Nazan GÜNEL, Ahmet ÖZET

Pages : 932-939

Doi:10.18621/eurj.1251443

View : 97 | Download : 129

Publication Date : 2023-09-04

Article Type : Research Paper

Abstract :Objectives: We analyzed the impact of some clinical and disease-specific factors on the longterm outcomes of SARS-CoV-2 infection in patients with solid tumors. Methods: Total of 739 patients with known solid malignancy and infected by SARS-CoV-2 before the beginning of vaccination were examined. Results: Seventy-six cancer patients died from COVID-19 infection-related effects such as mostly pulmonary and cardiovascular system disorders after a median 16-month follow-up insert ignore into journalissuearticles values(67.1% and 14.5%; respectively);. Compared with survivors insert ignore into journalissuearticles values(n = 468);, non-survivors due to COVID-19 infection related effects insert ignore into journalissuearticles values(n = 76); were more likely to be aged ≥ 65 years and diagnosis with lung cancer insert ignore into journalissuearticles values( p = 0.01);. Also, female patients were at decreased risk of mortality [OR: 0.34 insert ignore into journalissuearticles values(95% CI: 0.18-0.65);]. Furthermore, patients with tumor stage IV, active/stable/progressive disease and patients receiving active anticancer therapy were at increased risk of mortality insert ignore into journalissuearticles values( p = 0.01);. Conclusions: The patients with aged ≥ 65 years, diagnosed with lung cancer, receiving active anticancer therapy, with active/stable/progressive and advanced cancer stage were at increased risk of mortality from COVID-19 infection in long-term follow-up.
Keywords : Cancer patients, COVID 19, mortality, long term outcomes