Characterization of clinical features of monosensitized and polysensitized allergic rhinitis patients with pollen allergy

Authors : Şadan SOYYİĞİT, Dilek ÖKSÜZER ÇİMŞİR

Pages : 884-893

Doi:10.18621/eurj.1263071

View : 95 | Download : 157

Publication Date : 2023-09-04

Article Type : Research Paper

Abstract :Objectives: The present study evaluates the prevalence of monosensitization and polysensitization in patients with pollen-hypersensitive moderate-to-severe persistent allergic rhinitis insert ignore into journalissuearticles values(AR);, and determines the clinical characteristics of the two phenotypes. Methods: This retrospective cohort study included 160 patients with moderate-to-severe persistent AR among the 3,699 patients who presented to allergy outpatient clinics who were found to have hypersensitivity to pollen based on a skin prick test and/or allergen-specific IgE positivity. The patients were divided into two groups: monosensitized insert ignore into journalissuearticles values(hypersensitivity to pollen alone);, and polysensitized insert ignore into journalissuearticles values(hypersensitivity to pollen and other allergens);. Both groups were evaluated for allergen hypersensitivity, symptoms of AR, symptom frequency and comorbidities related to AR. Results: Of the 160 patients, 83 insert ignore into journalissuearticles values(51.9%); were monosensitized and 77 insert ignore into journalissuearticles values(48.1%); were polysensitized. The mean age was 29.5 ± 10.7 yeasrs and 28.3 ± 8.3 years, respectively and the female-to-male ratio was 42/41 and 47/30 in the two groups. Nasal congestion was remarkably more common in the polysensitized patients than in the monosensitized patients insert ignore into journalissuearticles values( p = 0.01);. Hypersensitivity to weed mix and Cupressus arizonica pollen identified with a skin prick test was significantly more common in the polysensitized patients than in the monosensitized patients insert ignore into journalissuearticles values( p = 0.03 and p = 0.01, respectively);. The two groups were similar in terms of the prevalence of asthma and other comorbidities related to rhinitis insert ignore into journalissuearticles values( p = 0.78);. Conclusions: In this single-center study, the rates of monosensitization and polysensitization were found to be similar in patients with pollen-hypersensitive moderate-to-severe AR, and the clinical characteristics of the polysensitized phenotype were different from those of the monosensitized phenotype.
Keywords : Pollen allergy, allergic rhinitis, monosensitization, polysensitization, skin prick test