Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.

Authors : Sinem BALTACI, Hatice Efsun KOLATAN, Osman YILMAZ, Bijen KIVÇAK

Pages : 757-762

View : 16 | Download : 11

Publication Date : 2011-12-01

Article Type : Research Paper

Abstract :Ethanolic insert ignore into journalissuearticles values(EEAA); and sesquiterpene lactone insert ignore into journalissuearticles values(SEAA); extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. insert ignore into journalissuearticles values(Asteraceae); were evaluated for anti-inflammatory activity on carrageenin-induced paw edema insert ignore into journalissuearticles values(acute model); and cotton pellet-induced granuloma insert ignore into journalissuearticles values(chronic model); in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.
Keywords : Key words Anthemis aciphylla, anti inflammatory activity, carrageenin, paw edema, cotton pellet