The Effects of Oral Administration of an Aqueous Extract of Ficus bengalensis Stem Bark on Some Hematological and Biochemical Parameters in Rats with Streptozotocin-Induced Diabetes

Authors : Mahalingam GAYATHRI, Krishnan KANNABIRAN

Pages : 9-13

View : 18 | Download : 10

Publication Date : 2009-12-01

Article Type : Research Paper

Abstract :The effects of sub-chronic administration of an aqueous extract of Ficus bengalensis stem bark on hematological and biochemical parameters in rats with streptozotocin insert ignore into journalissuearticles values(STZ);-induced diabetes were evaluated. The possible protective effect of the F. bengalensis insert ignore into journalissuearticles values(500 mg/kg of body weight per day); extract on STZ-induced changes was evaluated over 12 weeks. The parameters evaluated were plasma proteins, including total protein albumin and globulin, non-protein nitrogenous substances, including urea, uric acid, and creatinine, and hematological indices, including total hemoglobin content, erythrocytes, leucocytes, and platelets counts. The aqueous extract had a significant insert ignore into journalissuearticles values(P < 0.05); protective effect against STZ-induced changes in terms of the markers of protein metabolism and hematological indices. Furthermore, increases in levels of non-protein nitrogenous substances were normalized in response to the administration of the extract. Thus, the aqueous extract of F. bengalensis had a significant protective effect on STZ-induced changes to biochemical and hematological parameters in the diabetic rats.
Keywords : Ficus bengalensis, streptozotocin, non protein nitrogenous substances, hematological indices