ABO, Rh Blood Groups and Phosphoglucomutase 1 Enzyme Phenotypes in Individuals With Noninsulin Dependent Diabetes Mellitus

Authors : E Ferda PERÇİN, İsmihan GÖZE

Pages : 1-8

View : 30 | Download : 9

Publication Date : 1999-12-01

Article Type : Research Paper

Abstract :An examination of the relationships between common diseases and polymorphism may facilitate a better understanding of the clinical variability of illnesses and their genetic bases. In this paper, the relationship between blood group and erythrocyte phosphoglucomutase 1 insert ignore into journalissuearticles values(PGM1); enzyme phenotype and noninsulin-dependent diabetes mellitus insert ignore into journalissuearticles values(NIDDM); was investigated. The enzyme phenotypes of 205 diabetic individuals were determined using the agglutination method. The results were compared with data from 200 subjects in the control group. When the diabetic individuals and those in the control group were compared according to PGM1 phenotype, no statistically significant difference between the two was observed insert ignore into journalissuearticles values(p>0.05);. However, in ABO and Rh phenotypes the difference was found to be significant insert ignore into journalissuearticles values(p
Keywords : Diabetes Mellitus, PGM1, enzyme polymorphism, ABO, Rh