N -functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies

Authors : Yetkin GÖK, Senem AKKOÇ, Özlem Özeroğlu ÇELİKAL, İlknur ÖZDEMİR, Selami GÜNAL, Elif SAYIN

Pages : 1007-1013

Doi:10.3906/kim-1304-72

View : 23 | Download : 10

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene insert ignore into journalissuearticles values(NHC); precursors were treated with Ag2CO3 to yield silverinsert ignore into journalissuearticles values(I);-NHC complexes insert ignore into journalissuearticles values(1a--g); in dichloromethane as a solvent at room temperature. The 7 new silver-NHC complexes were fully characterized by means of 1H NMR, 13C NMR, and elemental analysis techniques. Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains insert ignore into journalissuearticles values(Pseudomonas aeruginosa and Escherichia coli);, 2 gram-positive bacterial strains insert ignore into journalissuearticles values(Enterococcus faecalis and Staphylococcus aureus);, and 2 fungi insert ignore into journalissuearticles values(Candida tropicalis and Candida albicans);.
Keywords : N Heterocyclic carbene, benzimidazol 2 ylidene, silver complex, antimicrobial activity, medical inorganic chemistry