Synthesis of 3,4-diaryl-1-phenyl-4,5-dihydro-1H -pyrazole-5-carbonitriles via 1,3-dipolar cycloaddition reactions

Authors : Jayaroopa PRABHASHANKAR, Vasanth Kumar GOVINDAPPA, Ajay Kumar KARIYAPPA

Pages : 853-857

Doi:10.3906/kim-1209-52

View : 16 | Download : 10

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Nitrile imines generated by the oxidative dehydrogenation of aromatic aldehyde phenylhydrazones with chloramine-T as a catalytic dehydrogenating agent were trapped in situ by 4-methoxy cinnamonitrile to afford 3,4-diaryl-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitrile in moderate to good yields. The structures of the cycloadducts were confirmed by spectral studies and elemental analysis.
Keywords : Pyrazoles, nitrile imines, chloramine T, dipolar, cycloaddition