Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings

Authors : Tarik ElSayed ALI, Salah AbdelAziz ABDELGHAFFAR, Kamilia Mohamed ELMAHDY, Somaia Mohamed ABDELKARIM

Pages : 160-169

Doi:10.3906/kim-1205-18

View : 14 | Download : 7

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A simple synthetic method is reported for the preparation of some new phosphorus macrocycles in which the pyrazole rings are appended to a phosphorus atom. The methodology is based on the cyclocondensation reaction of bisinsert ignore into journalissuearticles values(4-formylpyrazolyl); phosphine oxideinsert ignore into journalissuearticles values(1a, 1b); with nitrogen nucleophiles that contain active terminal amino groups. The antimicrobial activities of the synthesized compounds were assayed.
Keywords : Key words Phosphorus macrocycles, pyrazole, cyclocondensation, nitrogen nucleophiles