A one-pot efficient four-component reaction for the synthesis of 2-(arylamino)-2-(5-aryl-1-ethenyl-1,3,4-oxadiazol-2-yl)propyl benzoate (or 4-bromobenzoate) derivatives

Authors : Mohsen VALIZADEH HOLAGH, Abel Mohammadalioglu MAHARRAMOV

Pages : 671-681

Doi:10.3906/sag-1203-69

View : 16 | Download : 10

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Reactions of N-isocyaniminotriphenylphosphorane with 2-oxopropyl benzoate insert ignore into journalissuearticles values(or 2-oxopropyl 4-bromobenzoate); in the presence of 3-phenyl-2-propynoic acid and primary amines proceeded smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeded smoothly and cleanly under mild conditions and no side reactions were observed.
Keywords : 2 Oxopropyl benzoate, 2 oxopropyl 4 bromobenzoate, 3 phenyl 2 propynoic acid, 1, 3, 4 oxadiazole, N isocyaniminotriphenylphosphorane