Synthesis and antimicrobial activity of some novel 4-hydroxyquinolin-2(1H)-ones and pyrano[3,2-c] quinolinones from 3-(1-ethy1-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-3-oxopropanoic acid

Authors : Hany Mohamed HASSANIN, Magdy Ahmed IBRAHIM

Pages : 682-699

Doi:10.3906/tar-1301-112

View : 22 | Download : 11

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Chlorination, bromination, and condensation reactions of 3-insert ignore into journalissuearticles values(1-ethy1-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl);-3-oxopropanoic acid insert ignore into journalissuearticles values(3); were studied. Some novel 4-hydroxyquinolin-2insert ignore into journalissuearticles values(1H);-ones and pyrano[3,2-c]quinolin-2insert ignore into journalissuearticles values(1H);-ones were also prepared. The structures of the novel compounds were established by elemental analyses and spectral data. All the products were also screened in vitro for their antimicrobial activity.
Keywords : b Ketoacid, 4 hydroxyquinolin 2 1H, one, pyrano 3, 2 c quinolinone, condensation reactions