Three-component Passerini-Smiles coupling reaction of aldehydes and isocyanides with tropolone catalyzed by silica nanoparticles

Authors : Abdolhossain MASSOUDI, Issa AMINI, Ali RAMAZANI And

Pages : 537-544

Doi:10.3906/vet-1302-50

View : 19 | Download : 12

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The use of Smiles rearrangement in Passerini-type couplings with tropolone allows very straightforward multicomponent formation of a-aryloxy amide derivatives. The 3-component addition of isocyanide to tropolone insert ignore into journalissuearticles values(2-hydroxy-2,4,6-cycloheptatrien-1-one); and aldehyde in the presence of silica nanoparticles insert ignore into journalissuearticles values(silica NP, ca. 70 nm); proceeds easily in methanol to form the title compounds in a new Passerini-Smiles-type reaction.
Keywords : Smiles rearrangement, Passerini type coupling, tropolone, isocyanide, silica nanoparticles, Passerini Smiles type reaction