Ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates as sources of imidazopyrimidine and aminoindole derivatives

Authors : Ahmad POURSATTAR MARJANI, Jabbar KHALAFY

Pages : 847-858

Doi:10.3906/sag-1207-10

View : 13 | Download : 8

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The reaction of ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates with 2-chloropyrimidine and 2-chlorobenzoxazole gave the corresponding isoxazolones with pyrimidine and benzoxazole rings substituted on N-2. Their rearrangements with triethylamine in ethanol produced the corresponding imidazopyrimidine and aminoindole derivatives, respectively, through intramolecular cyclisation.
Keywords : Isoxazolones, 2 chloropyrimidine, 2 chlorobenzoxazole, rearrangements, imidazopyrimidines, aminoindoles