Radical scavenging potential of compounds isolated from Vitex agnus-castus

Authors : Talat MAKHMOOR, AZIZUDDIN, Muhammad İqbal CHOUDHARY

Pages : 119-126

View : 15 | Download : 8

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Nine secondary metabolites-artemetin insert ignore into journalissuearticles values(1);, casticin insert ignore into journalissuearticles values(2);, 3-hydroxy-5,6,7,4`-tetramethoxy flavone Uinsert ignore into journalissuearticles values(3);, penduletin insert ignore into journalissuearticles values(4);, p-hydroxybenzoic acid insert ignore into journalissuearticles values(5);, methyl 3,4-dihydroxybenzoate insert ignore into journalissuearticles values(6);, methyl isovanillate insert ignore into journalissuearticles values(7);, vanillic acid insert ignore into journalissuearticles values(8);, and 3,4-dihydroxybenzoic acid insert ignore into journalissuearticles values(9);-were isolated from a folkloric medicinal plant, Vitex agnus-castus. The structures of compounds 1-9 were identified using spectroscopic techniques. Compound 7 was isolated for the first time from this plant. These compounds were screened for their antioxidant activity. Compounds 6 and 9 exhibited significant activity against the DPPH free radical.
Keywords : Vitex agnus castus, Verbenaceae, antioxidant, DPPH radical scavenging activity, flavonoids