Synthesis and single crystal structure analysis of three novel benzoylthiourea derivatives

Authors : Gülten KAVAK, Süheyla ÖZBEY, Gün BİNZET, Nevzat KÜLCÜ

Pages : 857-868

View : 17 | Download : 10

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :N,N-dimethyl-N` -insert ignore into journalissuearticles values(2-methylbenzoyl);thiourea, C11H14N2SO insert ignore into journalissuearticles values(HL1);, N,N-dibutyl-N` -insert ignore into journalissuearticles values(2-methylben\-zoyl);thiourea, C{17}H{26}N2SO insert ignore into journalissuearticles values(HL2);, and N,N-dihexyl-N` -insert ignore into journalissuearticles values(2-methylbenzoyl); thiourea, C{21}H{34}N2SO insert ignore into journalissuearticles values(HL3); were synthesized and characterized by elemental analysis, spectroscopic methods insert ignore into journalissuearticles values(FT-IR, NMR);, and single crystal X-ray diffraction. Compound HL1 crystallizes in the monoclinic system, space group P21/c, Z = 4. Compound HL3 also crystallizes in the monoclinic system, space group P21/n, Z = 8 with 2 independent molecules in the asymmetric unit. Compound HL2 crystallizes in the orthorhombic system, space group Pcnn, Z = 8. In all compounds, molecules form dimers through the strong intermolecular N-H...S hydrogen bonds. Moreover, there are different types of intra- and inter-molecular interactions in the crystal structures, and so the molecules of the 3 compounds also pack differently.
Keywords : Thiourea derivatives, benzoylthioureas, single crystal X ray structures