Synthesis, X-ray Structure, and Bioassay of Newly Synthesized Trimethyltin(IV) 2,3-Methylenedioxy Benzoate

Authors : Mukhtiar HUSSAIN, Muhammad HANIF, Saqib ALI

Pages : 25-33

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Trimethyltininsert ignore into journalissuearticles values(IV); complex containing the carboxylate ligand 2,3-methylenedioxybenzoic acid insert ignore into journalissuearticles values(HL); have been synthesized and characterized in solution state by multinuclear NMR insert ignore into journalissuearticles values(1H, 13C and 119Sn); using the noncoordinating solvent and also in solid sate by FTIR, mass spectrometry, and X-ray crystallography. Spectroscopic data have shown that methylenedioxy moiety has not coordinated with tin atom; instead, the coordination site is a -COO group, which is proved by spectral and XRD data. The solid state structure shows the trigonal bipyramidal geometry with a space group P21/c. This compound was tested for its in vitro antitumor activity.
Keywords : 2, 3 methylenedioxybenzoic acid, spectroscopy, X ray structure, antitumor activity