Synthesis of New Bengazole Analogues and Their Antimicrobial Activity

Authors : Jürgen KRAUSS, Sandra KALKBRENNER, Angela SCHUSTER

Pages : 125-130

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Bengazole A and bengazole B are 2 representatives out of a large family of marine metabolites isolated from a Jaspis sponge and display potent anti-fungal and anthelmintic activity as well as modest cytotoxic activity. This paper reports a short and efficient synthesis and microbiological evaluation of some new bengazole analogues.
Keywords : Bengazole, lithiation, antimicrobial activity, cytotoxicity